Oral semaglutide: a once-a-day GLP-1 option, prescribed online
A daily oral GLP-1 option for weight management, with unlimited provider visits and 1-on-1 coaching, for $197 a month. Available in every state except Louisiana.
See plans & start my assessment →Exact price is shown before you pay. No hidden fees.What is oral semaglutide?
Oral semaglutide is semaglutide taken by mouth once a day instead of as a weekly injection. Semaglutide is a GLP-1 receptor agonist that slows how quickly your stomach empties and acts on appetite signals. Some people prefer a daily oral option because they would rather not inject.
Semaglutide taken by mouth has been studied in clinical trials for weight management. In one large trial, adults taking a daily oral semaglutide tablet alongside lifestyle changes lost more weight on average than adults on a placebo. That trial studied an FDA-regulated tablet at a set dose, not a compounded preparation. Results vary from person to person.
Oral semaglutide through Living+
About compounded medication. Some medications prescribed through Living+ are compounded. Compounded drugs are not FDA-approved. The FDA does not review them for safety, effectiveness or quality before they are sold. They are prepared by a licensed pharmacy for one patient, on a prescription. They are not generic versions of any brand-name medicine. A compounded preparation is prescribed only when your provider decides an FDA-approved product is not clinically suitable for you, and your provider records the reason in your chart.
How you take it matters. Some oral semaglutide products must be taken on an empty stomach with only a small amount of water, and you then wait before eating, drinking or taking other medicines. Follow the instructions on your pharmacy label exactly, and ask your care team if anything is unclear.
Oral vs injection
| Oral semaglutide | Semaglutide injection | |
|---|---|---|
| How often | Once a day | Once a week |
| How taken | By mouth, following label timing rules | Small injection under the skin |
| Living+ price | $197 a month | $197 a month |
| Who decides | Your provider, based on your health history and preference | |
Learn more about the injection on our semaglutide page.
Oral semaglutide cost with Living+
Oral semaglutide is $197 a month, flat. That includes:
- Your medication, if your provider prescribes it, shipped to you
- Provider care, with unlimited provider visits at no extra cost
- Labs, when your provider orders them
- Two private 1-on-1 coaching sessions a month
- Certified medical assistants and registered nurses on call 24/7, every day of the year
- Patient support by chat, email and phone, 24/7
- No separate visit fee, and no charge for extra provider visits.
- No surcharge when your provider changes your dose.
- If a provider decides not to prescribe, you get a full refund.
- Monthly subscription. Pause or cancel any time.
- Self-pay. Living+ does not bill insurance.
Start with a short online assessment. A licensed provider reviews it and decides whether treatment is right for you.
See plans & start my assessment →Who oral semaglutide may be right for
Your provider uses the same kind of criteria as for injectable GLP-1 medicines (BMI and weight-related conditions) together with your full health history, and takes your preference for a daily oral option into account.
GLP-1 treatment through Living+ is available in every state except Louisiana.
Side effects and safety
The most common side effects of GLP-1 medicines are stomach-related: nausea, diarrhea, vomiting, constipation and stomach pain. They are usually worst when you start or when the dose goes up. Tell your provider about any side effect, and get medical help right away for severe stomach pain that does not go away, signs of an allergic reaction, or very little urine.
Important: FDA-approved semaglutide and tirzepatide carry a boxed warning about thyroid C-cell tumors seen in rodent studies. Do not use these medicines if you or anyone in your family has had medullary thyroid carcinoma (MTC), or if you have multiple endocrine neoplasia syndrome type 2 (MEN 2). Other serious risks include pancreatitis, gallbladder problems, low blood sugar (especially with insulin or a sulfonylurea), kidney problems from dehydration, and allergic reactions. These medicines are not for use during pregnancy. See our Important Safety Information.
Frequently asked questions
Is there a GLP-1 pill I can get online?
Living+ offers oral semaglutide, taken by mouth once a day, in every state except Louisiana. A licensed provider reviews your online assessment and decides whether it is appropriate for you.
How much does oral semaglutide cost?
Oral semaglutide through Living+ is $197 a month, flat, including provider care, unlimited visits, labs when ordered, coaching and 24/7 care-team support.
Is oral semaglutide from Living+ FDA-approved?
Some medications prescribed through Living+ are compounded, and compounded drugs are not FDA-approved. Your pharmacy label shows exactly what you receive. Ask your provider if you have questions.
How do I take oral semaglutide?
Follow your pharmacy label. Some oral semaglutide products must be taken on an empty stomach with a small sip of water, with a wait before eating or taking other medicines.
Sources
- MedlinePlus (U.S. National Library of Medicine). Semaglutide injection. medlineplus.gov
- DailyMed (U.S. National Library of Medicine). FDA prescribing information for semaglutide products. dailymed.nlm.nih.gov
- Knop FK, et al. Oral semaglutide 50 mg taken once per day in adults with overweight or obesity (OASIS 1). Lancet. 2023;402:705-719. pubmed.ncbi.nlm.nih.gov
- National Institute of Diabetes and Digestive and Kidney Diseases. Prescription medications to treat overweight & obesity. www.niddk.nih.gov
- U.S. Food and Drug Administration. FDA's concerns with unapproved GLP-1 drugs used for weight loss. www.fda.gov
Living+ Rx connects patients with licensed providers who determine whether a prescription is appropriate. Treatment is not guaranteed. Some medications offered may be compounded; compounded drugs are not FDA-approved and are prepared by a licensed pharmacy for an individual patient. Discuss risks and benefits with your provider.
Care coaching is educational, non-clinical support and is not a substitute for medical care, registered-dietitian services, or mental-health therapy.
This page is general information, not medical advice. Prices were accurate at the time this was published; the exact price is always shown before you pay.